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Tirzepatide is a novel glucagon-like peptide-1 (GLP-1), gastric inhibitory peptide (GIP), and glucagon triple agonist that has been developed for the treatment of type 2 diabetes.

GLP-1 and GIP are two hormones that are naturally produced in the gut and play important roles in regulating blood sugar levels and appetite. They work by stimulating the release of insulin from the pancreas and reducing the production of glucose in the liver. Additionally, they can also slow down the movement of food through the stomach and small intestine, which can help to promote feelings of fullness and reduce food intake.

Glucagon, on the other hand, is a hormone that raises blood glucose levels by stimulating the liver to produce glucose. In Tirzepatide for weight loss, the combination of GLP-1, GIP, and glucagon is designed to provide a more comprehensive approach to blood sugar regulation, as it simultaneously stimulates insulin production, reduces glucose production, and promotes feelings of fullness, while also maintaining blood glucose levels within a healthy range.

Overall, Tirzepatide's mechanism of action is aimed at improving glycemic control and promoting weight loss. In a clinical trial, Tirzepatide was found to induce significant weight loss in obese patients (BMI of 30+), with an average weight loss of 13.3% over 26 weeks. Tirzepatide was also shown to improve glycemic control and reduce cardiovascular risk factors such as blood pressure and cholesterol levels.


Tirzepatide for weight loss may have potential side effects and should only be used under the guidance of a healthcare professional. Some side effects that have been reported are:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Dizziness
  • Fatigue
  • Decreased appetite.
  • Hypoglycemia (low blood sugar)
  • Injection site reactions (if administered by injection)

It is important to note that not everyone who takes Tirzepatide will experience side effects, and the severity and duration of side effects may vary depending on the individual. It is also possible that other side effects may be identified as more data becomes available from ongoing studies.

If you are considering taking Tirzepatide or have any concerns about potential side effects, it is important to discuss this with your healthcare provider. They can provide you with more information on the benefits and risks of the medication and help you make an informed decision about your treatment options.

What is the difference between Tirzepatide and Semaglutide? 

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Tirzepatide Starter Program 1mL-5mg/.5mL

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